Boronate Affinity Method POCT HbA1c Analyzer 2 Minutes Whole Blood Sample Type

POCT HbA1c Analyzer Bronate Affnity Fluorescence Quenching Principle For Glycosylated Hemoglobin Test​

POCT HbA1c Analyzer Bronate Affnity Fluorescence Quenching Principle For Glycosylated Hemoglobin Test is intended for detecting glycoslated hemoglobin (HbA1c) in human blood.

According to the most recent IDF data, 537 million people—approximately 10% of all people aged 20-79 in the world—were living with diabetes as of 2021.

Specification

Principle

The analyzer works based on the principle of boric acid affinity fluorescence quenching. The content of HbA1c is quantitatively detected by detecting the amount of fluorescent substance changing with the binding and quenching of HbA1c and fluorescent substance.

The Application of Boronate affinity in Individual Test Cartridge POCT HbA1c Analyzer For Glycosylated Hemoglobin Test.

After the magnetic beads are pushed into the kit, the borate in the reagent binds to the fluorophore in the magnetic beads, resulting in a large amount of excited fluorescence

After the magnetic beads are pushed into the kit, the borate binds to the fluorophore, producing a large amount of excited fluorescence.

After the sample is added to the reagent, the borate-fluorophore competes with hemoglobin for binding, resulting in a decrease in fluorescence. Because the binding force of unglycated hemoglobin is much greater than that of glycated hemoglobin, the unglycated hemoglobin first binds to the borate-fluorophore, resulting in a sharp drop in fluorescence. The content of unglycated components can be detected during this process.

Next, the glycosylated hemoglobin is bound to a borate-fluorophore. This binding process is slow and therefore the fluorescence quenching process is slow and curvilinear. The fluorescence quenching process in the detection cycle of the instrument can reflect the content of glycosylated hemoglobin.

Feature

• Boronate affinity Method: The HbA1c assay has no interference from common Hb variants

• Ease of use: One-step operation the instrument is ready for use.

• Less than 3-minute test time

• A compact, lightweight instrument, Compact Size - To Minimize Space Requirements.

• With no need for bulky liquid reagents, LD-100 also free up more space in laboratories, clinics, blood banks, and other situations.

• Traceable to the IFCC Reference Method for HbA1c；Results reporting unit: IFCC units (mmol/mol) and NGSP units (%%).

Certificate

Labnovation Technologies, Inc. is an original manufacturer established in Shenzhen, China since 2001. We are dedicated in developing and manufacturing IVD instruments and reagents including HbA1c analyzer and reagents, rapid test reader & reagents, hematology reagents, clinical chemistry reagents, electrolyte reagents, wash solution and urine test reagents.

Labnovation products are developed in house, tested extensively in clinics and passed strict quality controls. All of our products are CE marked and approved by SFDA. In the past 15 years, our products have been exported to 110 different countries and used in 8000 hospitals worldwide. We provide both ready-to-use final products and bulk OEM reagents, including ready-to-use reagents, concentrated, and powder.

With an investment of 10% of our annual sales into R&D, we release new products every years. We win more and more domestic and international cooperation by company reputation and products quality while we actively take part in fairs like MEDICA,AACC, ARBA HEALTH and so on through which we are well-known by the companies in this field.