China Largest Factory Manufacturer PICEATANNOL CAS 10083-24-6 For stock delivery
Brand Name:Leader
Certification:ISO,GMP,SGS,HALA,KOSER,HACCP
Model Number:LD
Minimum Order Quantity:25KGS
Delivery Time:2-3 working days
Payment Terms:Western Union, MoneyGram, T/T, L/C
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| PICEATANNOL Basic information |
| Product Name: | PICEATANNOL |
| Synonyms: | TRANS-3,3',4,5'-TETRAHYDROXYSTILBENE;PICEATANNOL;PICEATANNOL (3,3',4,5'-TETRAHYDROXY-TRAN;(e)-4-[2-(3,5dihydroxyphenyl)nyl]1,2-benzenediol;4-[2-(3,5-dihydroxyphenyl)nyl]benzene-1,2-diol;trans-Piceatannol;(E)-3,3',4,5'-Tetrahydroxystilbene;(E)-Piceatannol |
| CAS: | 10083-24-6 |
| MF: | C14H12O4 |
| MW: | 244.24 |
| EINECS: | 600-132-4 |
| Product Categories: | Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;Stilbenes (substituted);Protein Kinase;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Syk;Inhibitors |
| Mol File: | 10083-24-6.mol |
| PICEATANNOL Chemical Properties |
| Melting point | 223-227 °C |
| Boiling point | 108°C/0.04mmHg(lit.) |
| density | 1.1245 (rough estimate) |
| refractive index | 1.5190 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 0.5 mg/mL |
| pka | 9.17±0.10(Predicted) |
| form | powder |
| color | light tan to yellow |
| λmax | 323nm(MeOH)(lit.) |
| Safety Information |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29072990 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| PICEATANNOL Usage And Synthesis |
| Description | Piceatannol is a chemical compound with similar structure to
resveratrol, being widely existed in vegetables such as grapes,
blueberries and passion fruit. It is capable of inhibiting the
growth of immature adipocytes, so as to achieve the purpose of
weight loss. In addition, it also helps prevent cancer, heart
disease and neurological diseases. In early April 2012, researchers in Purdue University has published a new study in journal, finding that piceatannol can delay the production of new fat cells, and inhibit the growth of immature fat cells into mature cells, which can help control the obesity. The researchers also claim that while this study shows that red wine helps to lose weight, further research is needed to improve the stability and solubility of the white fat to maximize its effect. Laboratory preparation: 3, 4-dibenzyl alcohol is used as the starting material; to obtain the target product; the raw material needs to undergo bromination, Arbuzov rearrangement reaction, Wittig-Horner reaction and demethylation reaction. |
| Application | Antioxidants, having anti-inflammatory, anti-thrombotic, anti-cancer, anti-cancer, anti-hyperlipidemia, anti-bacterial activities. |
| Chemical Properties | yellow to golden or green crystalline powder |
| Uses | A human metabolite of Resveratrol (R150000). |
| Definition | ChEBI: A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5. |
| Biological Activity | Anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56 lck and syk protein tyrosine kinases and inhibits TNF-induced NF- κ B activation and gene expression. Synthesis results from conversion of resveratrol (5-[(1E)-2-(4-Hydroxyphenyl)nyl]-1,3,benzenediol ) by cytochrome P450 1B1. |
| PICEATANNOL Preparation Products And Raw materials |
China Largest Factory Manufacturer PICEATANNOL CAS 10083-24-6 For stock delivery
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