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Luteinizing hormone is a type of glycoprotein gonadotropin secreted by basophilic cells of the pituitary gland. It primarily promotes ovulation. Under the synergistic action of FSH, luteinizing hormone is formed and progesterone is secreted. In general, the normal value during the non-ovulatory period is 5-25 mIU/ml and lower than 5mIU/ml indicates insufficient gonadotropin function, which can be seen in Sheehan's syndrome. High FSH and elevated LH indicate a decrease in ovarian function, and LH/FSH ≥ 3 is one of the bases for diagnosing polycystic ovary syndrome.
Detection range | sample size | Sample type | Test time |
0.2~160mIU/mL | 60μl | Whole blood / serum / plasma | 15min |
Corresponding items | index | Guiding significance | |
FSH,LH | ↑ | Common in primary gonadal lesions | Such as premature ovarian failure, gonadal dysplasia, primary amenorrhea, major sexual hypofunction, disturbed development of the convoluted seminiferous canal, complete (true) premature sexual |
↓ | Mostly seen in pituitary or hypothalamic amenorrhea, incomplete (pseudo) pre-sexual. | ||
Pituitary FSH tumor or LH tumor | Depending on the tumor type, FSH and LH concentrations vary from type to type. | FSH tumors mainly show elevated FSH and normal LH. Among patients with LH tumors, LH was significantly higher and FSH was lower. | Both FSH and LH were elevated among patients with FSH/LH tumors. |
Concentrations of FSH and LH in postmenopausal women | Differentiate effectively between ovarian menopause and somatic or glomerular menopause |
Gynecology, obstetrics and gynecology, laboratory science, oncology, reproductive medicine, genetics, etc.
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