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Description:
12 Channel Oligo Synthesizer is a laboratory instrument used to synthesize DNA or RNA sequences, often referred to as oligos, which are typically short strands of nucleotides. The English specifications for such a device might include:
Channels: The synthesizer has 12 independent synthesis channels, allowing for the simultaneous synthesis of up to 12 unique oligonucleotides, thereby improving lab efficiency.
Synthesis Capabilities: It can synthesize oligos ranging from a few bases to hundreds of bases in length with high accuracy and purity, usually at a scale suitable for molecular biology applications (e.g., PCR primers, probes, siRNA).
Automation: Automated synthesis process with computer-controlled software that allows for precise control over reagent delivery, coupling time, and detritylation steps.
Chemistry Support: Supports standard phosphoramidite chemistry for DNA/RNA synthesis, with options for modified nucleotides if applicable.
Column Configuration: Each channel has its own dedicated synthesis column or reactor where solid-phase synthesis occurs.
Precision Dispensing: Advanced dispensing systems ensure accurate delivery of reagents including acylating agents, activators, and deprotection solutions.
Cleavage and Deprotection: In-built or external cleavage and deprotection modules for finalizing the synthesized oligos.
Washing System: A thorough washing system between each synthesis cycle to ensure high-quality products.
Control Software: User-friendly software interface for designing and programming the synthesis, monitoring progress, and analyzing results.
Quality Control: May include features like real-time UV monitoring for quantification and quality assessment during synthesis.
Compatibility: Compatibility with various types of resins for solid-phase synthesis, and potentially with different scales of synthesis (microscale to small scale).
Safety Features: Integrated safety measures such as fume hood compatibility, waste disposal systems, and error alerts to minimize risk and ensure user safety.
Specification:
Channel | 12 | Synthesis type | DNA/RNA.fluorescent dyes/sulfurizing/Probe |
Mode | reagent injection separately | period(20 mer) | 12 primers of 20bp with 2.5h |
Cycled Time | 4-6min | synthesis range | 25nmol-300umol |
Coupling rate | >99% | max length of primer | 120bp |
Bearing method | Synthetic column | wastes | vacuum |
base/reagent pouring mode | reagent injection separately | base/reagent drive way | protected gas press out |
Base cylinder quantities | Standard 12 pcs,20pcs optional | reagent bottle quantities | 7 pcs |
reagent cylinder configuration | single standard. double optional | reagent specifications | 450ml/4L |
synthesis merger base | Automatic merge the base | System | Win7 |
Data import method | Automatic by Excel | reagent generality | general |
Gas needed | Nitrogen or Argon | color | Matte Black |
reagent pipe dimension | OD1/8' and ID/16' | base pipe dimension | OD1/16, ID0.8mm |
outsize | 910*650*540mm | package size | 1200*700*600mm |