ESR & Erythrocyte Sedimentation Rate & Anticoagulation & Standardized Testing
Brand Name:Orsin
Certification:ISO 13485
Model Number:Gel Clot ActivatoR
Minimum Order Quantity:100/pcs
Delivery Time:1-4 weeks
Payment Terms:L/C, D/A, D/P, T/T, Western Union
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Location:
Shanghai Shanghai China
Address:
Building A, No.599 Wanhua Road, Zhelin Town, Fengxian Area, Shanghai, China
Supplier`s last login times:
within 1 hours
Product Details
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Product Details
Core Functions
Anticoagulation
Key additive: 3.2%–3.8% Sodium Citrate.
Blood-to-anticoagulant ratio: 4:1 (e.g., fill to "2mL" mark = 1.6mL blood + 0.4mL anticoagulant).
Mechanism: Chelates calcium ions → blocks coagulation cascade → maintains blood liquidity.
Standardized Testing
Specialized dimensions (Ø 2.5mm × 200mm) → Complies with Westergren method (ICSH standard).
Primary Applications
1. Monitoring Inflammatory Diseases
| Condition | Clinical Utility |
|---|---|
| Infections | Bacterial TB → ESR ↑↑ >100 mm/h |
| Autoimmune diseases | Active RA → ESR ↑ (combined with CRP) |
| Malignancies | Multiple myeloma → Persistent ESR ↑ (therapy monitor) |
2. Procedure (ICSH Protocol)
Fill blood to the calibration mark → 2. Invert mix 8 times → 3. Place vertically in Westergren rack → 4. Stand undisturbed at RT for 60 min → 5. Measure plasma interface drop (mm) = ESR value.
3. Result Interpretation
| ESR (mm/h) | Clinical Implication |
|---|---|
| <20 (M) / <30 (F) | Normal |
| 20–50 | Mild elevation (e.g., chronic inflammation) |
| >50 | Significant elevation (active infection/tumor) |
Critical Notes
1. Error Control
Fill volume deviation:
±10% error → ESR deviation up to 30% (Must fill exactly to the mark!).
Time sensitivity:
Test >4h post-collection → RBC morphology alters → Falsely ↓ESR.
2. Interfering Factors
| Factor | ESR Effect | Solution |
|---|---|---|
| Anemia (Hct<30%) | Falsely ↑ | Corrected ESR = ESR × [0.73+Hct] |
| Refrigerated sample | Falsely ↓ | Equilibrate to RT for 30 min |
| Underfilled tube | Clot formation | Discard and recollect |
ESR & Erythrocyte Sedimentation Rate & Anticoagulation & Standardized Testing
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