Factory Price Ultrafiltration unit for Separation of biological products 500 lters per hour water filtration system

Brand Name:HJW
Certification:ISO 14001,ISO 9001,CE,EPA
Minimum Order Quantity:1set
Delivery Time:1-7working days(depand on raw materials stocking)
Payment Terms:L/C,D/P,T/T,Western Union
Place of Origin:Shenzhen,Guangdong
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Location: Shenzhen China
Address: Room 1105, Building 3, Xinsheng Green Valley Industrial Park, Xinsheng Community, Longgang Street, Longgang District, Shenzhen,China
Supplier`s last login times: within 22 hours
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Product Details

I.Overview
Ultrafiltration (UF) assumes the core tasks of concentration, purification, buffer replacement and removal of impurities in the separation of biological products, and is especially suitable for the fine treatment of large molecules of biologically active substances (e.g. proteins, vaccines, nucleic acids). UF system is the gold standard of biologics separation, and its irreplaceable core value in biopharmaceuticals lies in: activity preservation, precise separation, and compliance guarantee.


II.Key technology flow
Typical route for downstream purification of monoclonal antibody:
cell culture solution → centrifugation/microfiltration → Protein A chromatography → virus inactivation → **UF/DF (ultrafiltration dialysis)** → purified chromatography → preparation


Plasmid DNA purification process:
bacteriophage lysis → alkaline extraction → ultrafiltration (100 kDa) → affinity chromatography → **tangential flow ultrafiltration (TFF)** → sterile filtration


III.Core Performance Parameters

ParameterStandard Requirement
Molecular Weight Cut - off1/3 - 1/6 of the target molecular weight (e.g., 30 kDa for monoclonal antibodies)
Recovery Rate> 95% (for monoclonal antibodies)
HCP Residue< 100 ppm
Endotoxin Removal< 0.001 EU/mg
Shear Force ControlLaminar shear force < 10 Pa·s


IV.Key Points for Equipment Selection

Membrane Module TypeApplicable Scenarios
Hollow FiberLarge - volume Processing (>500L)
Flat Sheet Membrane PackHigh - value - added Products (e.g., Gene Therapy)
Ceramic MembraneHigh - Viscosity/Particulate - containing Feed Liquid


V.Core Application Scenarios
Monoclonal Antibodies
Recombinant Proteins
Viral Vectors
Nucleic Acid Drugs
Vaccines


VI.Here is a guideline for you to get a proper quotation
Tell us the raw water/source of water(tap water, well water, or sea water, etc)
Provide water analysis report(TDS , conductivity, or resistivity, etc)
Required production capacity( 5m³/H, 50m³/H,or 500m³/H, etc)
What's the pure water used for( industrial,Food and Beverage,or agriculture, etc )


China Factory Price  Ultrafiltration unit for Separation of biological products 500 lters per hour  water filtration system supplier

Factory Price Ultrafiltration unit for Separation of biological products 500 lters per hour water filtration system

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