Hops Flower Extract Powder 1%-98% Xanthohumol
Brand Name:SL
Certification:ISO22000/ISO9001/HACCP/FDA
Model Number:SL25082804
Minimum Order Quantity:1kg
Delivery Time:3-5days
Payment Terms:T/T,alibaba,paypal
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What is Hops Flower Extract Xanthohumol?
Xanthohumol is a prenylated chalcone flavonoid compound extracted from hops, the only known natural source of xanthohumol. Its chemical structure can be derivatized to form active substances such as tetrahydroxanthohumol. Experimental studies have demonstrated multiple biological activities, including regulating lipid metabolism, inhibiting cancer cell proliferation, and slowing the progression of neurodegenerative diseases. Data from a 2023 publication in the journal Microbiome showed that its derivatives reduced low-density lipoprotein cholesterol levels by 80%, insulin levels by 42%, and the inflammatory marker interleukin-6 by 78% in experimental animals.
Key Features
1.Regulating Metabolic Function
Research has found that tetrahydroxanthohumol, by remodeling the
gut microbiome, reduced levels of the inflammatory factor IL-6 in
model animals by 78%.
2.Anti-Cancer Mechanism
Xanthohumol has a dual anti-cancer mechanism: on the one hand, it
inhibits the activity of carcinogenic enzymes such as
cyclooxygenase-2 (COX-2), and on the other hand, it directly
eliminates carcinogenic metabolites such as benzopyrene. In vitro
experiments showed that it inhibited the proliferation of the
breast cancer cell line MCF-7 by 65% (treatment with a 10μM
concentration for 72 hours).
3.Neuroprotective Effects
Xanthohumol enhanced the phagocytic capacity of microglia and
reduced the deposition of amyloid-β plaques by 42%. Subsequent
studies confirmed that this compound, by activating the Nrf2
pathway, increased the ability of neurons to resist oxidative
damage by 2.3%.
Product Parameters
| Analysis | Specification | Result |
| Physical Description | ||
| Appearance | Brown powder | Brown powder |
| Odor | Characteristic | Characteristic |
| Particle size | 100% pass 80 mesh | 100% pass 80 mesh |
| Chemical Tests | ||
| Assay (Extract ratio) | 10:01 | 10:01 |
| Loss on drying | 10.0% Max | <10.0% |
| Residue on Ignition | 10.0% Max | <10.0% |
| Heavy metals | 10.0ppm Max | <10.0ppm |
| As | 2.0ppm Max | <2.0ppm |
| Pb | 2.0ppm Max | <2.0ppm |
| Microbiology Control | ||
| Total plate count | 10,000cfu/g Max | <10,000cfu/g |
| Yeast & Mold | 1000cfu/g Max | <1000cfu/g |
| E. Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Conclusion | Complies with the standards. | |
Hops Flower Extract Powder 1%-98% Xanthohumol
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