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Thymidine Kinase (TK1)
Thymidine kinase 1 (TK1), a special kinase that catalyzes thymidine (TdR) to 1-phosphothymidylate (TMP), is an essential precursor for DNA synthesis in cancerous cells.
1. TK1 is a cell cycle-dependent enzyme that mainly exists in the cytoplasm. When a large number of proliferating cells appear in the body, the level of TK-1 increases ly. Once canceration occurs, along with the proliferation of tumor cells, the activity and content of TK-1 will increase, which can exceed the normal level by 20-100 times.
2. TK1 (cytoplasmic thymidine kinase 1) is an internationally
recognized marker of abnormal cell proliferation. It can detect the
level of thymidine kinase 1 (STK1) in serum, dynamically understand
the proliferation activity information of cancer cells in vivo, and
evaluate the therapeutic effect of tumors. , an earlier predictor
of tumor recurrence risk. Mainly used for: evaluating the effect of
surgery, monitoring the effect of chemotherapy, predicting the risk
of recurrence, and judging tumor prognosis, etc.
3. The application of TK1 to evaluate the effect of surgery. Scope
of application: tumor surgery of various parts. Recommended
monitoring points: 3 days or the same day before surgery, 7 days
after surgery; before discharge, or 30 days after surgery, and
before starting other treatments.
EXPLANATION OF THE TEST
TK1 is a cell cycle-dependent enzyme, mainly present in the
cytoplasm. When a large number of proliferating cells appear in the
body, the level of TK-1 increases ly. Once canceration occurs,
along with the proliferation of tumor cells, the activity and
content of TK-1 will increase, which can exceed the normal level by
20-100 times.
TK1 (cytoplasmic thymidine kinase 1) is an internationally
recognized marker of abnormal cell proliferation. It can detect the
level of thymidine kinase 1 (STK1) in serum, dynamically understand
the proliferation activity information of cancer cells in vivo,
evaluate the therapeutic effect of tumors, and more. early
predictor of tumor recurrence risk. Mainly used for: evaluating the
effect of surgery, monitoring the effect of chemotherapy,
predicting the risk of recurrence, and judging tumor prognosis,
etc.
Application of TK1 to assess surgical outcomes. Scope of
application: tumor surgery of various parts. Recommended monitoring
points: 3 days or the same day before surgery, 7 days after
surgery; before discharge, or 30 days after surgery, and before
starting other treatments.
Test item | TK1 |
Specification | 24 Test/Box for POClia |
Component | Magnetic Beads |
TK1 Anti | |
Substrate | |
Washing solution | |
Pipetting Tip | |
Magnetic Tube | |
Sample material | Serum |
Storage | 2-8℃ |
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GRP-17 |