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Pharmar Intermediates N-Methyl-D-aspartic Acid / DMDA CAS No.: 6384-92-5

Pharmar Intermediates N-Methyl-D-aspartic Acid / DMDA CAS No.: 6384-92-5

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Pharmar Intermediates N-Methyl-D-aspartic Acid / DMDA CAS No.: 6384-92-5


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Introduction:


Name:N-Methyl-D-aspartic acid
CAS No.: 6384-92-5
Molecular formular:C5H9NO4
Details of N-Methyl-D-aspartic acid
Superlist Name:N-Methyl-D-aspartic acid(NMDA)
Molecular Formula:C5H9NO4
CAS No.: 6384-92-5
Purity:99%
Synonyms:(R)-2-(Methylamino)succinic acid; NMDA
Molecular Weight:147.13
Appearance:white powder

Function :


N-Methyl-D-Aspartic acid (NMDA) is a water-soluble synthetic substance that is not normally found in biological tissue. It was first synthesized in 1960s. N-Methyl-D-Aspartic acid (NMDA) is an excitotoxin(it kills nerve cells by over-exciting them); this trait has applications in behavioral neuroscience research. The body of work utilizing this technique falls under the term "lesion studies."

Researchers apply N-Methyl-D-Aspartic acid (NMDA) to specific regions of an (animal) subject's brain or spinal cord and subsequently test for the behavior of interest, such as operant behavior. If the behavior is compromised, itsuggests the destroyed tissue was part of a brain region that made an important contribution to the normal expression of that behavior.

However, in lower quantities N-Methyl-D-Aspartic acid (NMDA) is not neurotoxic.

In fact, normal operation of the N-Methyl-D-Aspartic acid (NMDA) receptor allows individuals to respond to excitatory stimuli through the interrelated functioning of N-Methyl-D-Aspartic acid (NMDA) receptors, glutamate, and dopamine.

Therefore the action of glutamate specifically through N-Methyl-D-Aspartic acid (NMDA) receptors can be investigated by injecting small quantities of N-Methyl-D-Aspartic acid (NMDA) into a certain region in the brain: for example, injection of N-Methyl-D-Aspartic acid (NMDA) in a brainstem region induces involuntarylocomotion in cats and rats.

The mechanism of stimulating N-Methyl-D-Aspartic acid (NMDA) receptor is a specific agonist-binding to its NR2 subunits, and then a non-specific cation channel is opened, which can allow the passage of Ca2+ and Na+ into the cell and K+ out of the cell. The excitatory postsynaptic potential (EPSP) produced by activation of an N-Methyl-D-Aspartic acid (NMDA) receptor also increases the concentration of Ca2+ in the cell. The Ca2+ can in turn function as a second messenger in various signaling pathways.This process is modulated by a number of endogenous and exogenous compounds and play a key role in a wide range of physiological (e.g. memory) and pathological processes (e.g. excitotoxicity).

It has been deemed responsible for the incredible increase of hormonal output experienced during puberty, which results in rapid muscular and sexual development. This hormonal state is most desirable for building muscle mass and even useful in enhancing every aspect of sexual performance. This newly found receptor, when powerfully activated by amino acid based ingredient called N-Methyl-D-Aspartic acid (NMDA), elicits profound elevations of circulating anabolic hormones.There are studies showing it increases LH and test levels. N-Methyl-D-Aspartic acid (NMDA) receptor activation also plays a role in developing many neuro-degerative disorder like Parkinsons.


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We're specialized in pharma.raw materials ( hormone steroid powders, Steroids injectable liquids,peptides,Sarms), our company integrates R&D, producing, operating and marketing into an organic whole. We have authority of export and import, and have experience of export for 15 years.

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Pharmar Intermediates N-Methyl-D-aspartic Acid / DMDA CAS No.: 6384-92-5

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