English name: 2-Amino-N- [2-benzyloxy- (1 R) - [1- (methyl
sulfonyl) spiro [indoline-3,4'-piperidin] -1'-ylcarbonyl] ethyl]
Alias: Ibutamoren Mesilate; L-163191; MK-0677; MK-677; Crescendo; 1
'- (2-methylalanyl-O-benzyl-D-seryl) -1- (methylsulfonyl)
-1,2-dihydrospiro [indole- 3,4'-piperidine] methanesulfonate;
Molecular Weight: 624.7692
Nutrobal (Mk-677) is an orally administrated growth hormone
secretagogue originally developed by Reverse Pharmacology. A
secretagogue is the term for a substance that chemically signals
for the pituitary gland to secrete growth hormone. In other words,
Nutrobal could be compared to peptides like GHRP-6 or Ipamorelin,
only it doesn’t require any injections nor does it have any side
effects like GHRP-6. This GHS (Growth Hormone Secretagogue) was
developed in an aim to combat such conditions as muscle wasting,
obesity and osteoporosis. It was also targeted towards treatment of
elderly hip fracture patients, so there are a myriad of studies
done on safety.
How it Works
Growth hormone pulse intensity can be increased through 4 possible
- Increasing GHRH (growth hormone releasing hormone) release.
- Amplifying GHRH signaling in somatotrophs of the anterior pituitary
- Reducing somatostatin release (somatostatin turns off GH release).
- Inhibiting of somatostatin receptor signaling.
Nutrobal (Mk-677) was found to work through all four of these
mechanisms. After ingestion, Growth Hormone (GH) was shown to
increase dose dependently, at doses starting at 5 milligrams (mgs)
In a study on it’s effects on catabolic states, a once daily oral
dose of 25mgs was given to healthy young men subjected to
short-term diet-induced nitrogen wasting. After 7 days of this
dose, the subjects showed a sustained increase in serum
concentration of IGF-1 and Growth Hormone; in addition, the
nitrogen wasting was reversed, showing great potential for
treatment of conditions involving muscle wasting.
Trials testing the effects of this GHS on fighting obesity showed
an increase in lean body mass, but neither total, nor visceral
adipose tissue was effected. This study gave subjects 25mgs of
Nutrobal per day for 8 weeks. The subjects showed an increase in
basal metabolic rate after 2 weeks, and an increase in serum levels
of GH, IGF-1 and IGF-1 binding protein-3. Increase in lean body
mass was hypothesized to be caused by an increase in calorie
deposition into the muscle and appetite decrease as opposed to
reducing fat storage directly.
A study done for the treatment of osteoporosis and bone mineral
density showed some increase in bone density, so there is a true
impact on bone mineral density. This can help with injury recovery
during your cycle.
Other possible benefits of Nutrobal are associated with improved
sleep, improved complexion, increase in energy levels, increase
nitrogen retention, increase strength and an improved sense of well
being. In addition, some studies also suggest that an increased
immune system response was caused by Nutrobal (Mk-677), meaning it
boosts the immune system to a degree.
How can it help you?
Elevated growth hormone has literally endless list of benefits to
the human body, why do you think everyone tries to get their hands
on HGH? That’s why Nutrobal (Mk-677) is so effective, it increases
Growth Hormone and IGF-1 levels.
As the studies show, Nutrobal can be used for a number of reasons
from growing muscle mass, to getting shredded. It does not compete
with the levels of growth hormone one can get from exogenously
administered HGH, so you can use it with hgh cycles. In fact, by
using nutrobal, you can easily get amazing increases of your own
natural growth hormone pulses without having to deal with annoying
and painful daily HGH injections. It’s like using HGH without
having to inject daily.
In a multitude of studies, Nutrobal (Mk-677) increased IGF-1 levels
by between 39-89%. To give you an idea of what IGF-1 does, here are
some IGF-1 benefits:
- Increased Fat Oxidation (fat loss).
- Increased Muscle gains (lean mass).
- Tightening up loose skin.
- Healing old injuries.
- Healing Bones, Tendons and Ligaments.
In fact, many users report growing up to 6 lbs of lean muscle mass
in 8 weeks of IGF-1 only cycles. That’s an amazing result, but
injecting IGF-1 daily is painful, costly and frustrating. Now,
there is an oral-only alternative.
Here is an example of a Nutrobal + Cardarine + Andarine Cycle
|NOTE: Only ramp up andarine if you have the dosing schedule and
side effects schedule properly planned. Otherwise, stick to a lower
dose. See this andarine (s4) dosing schedule.|
ED = every day
mgs = milligrams
tabs = tablets
caps = capsules
This is an amazing cutting stack with Cardarine and Andarine, which
will help melt off the stubborn fat and increase your muscle mass.
Results have been shown from doses between 5-25mgs a day, dose
dependent results should be expected. Higher doses, over 50mgs,
have been reported by some, but I don’t see the need to overdo it.
Nutrobal (Mk-677) was found to be very safe and, in fact, showed to
reduce tumors in mice, which was hypothesized to be from an
increased immune system response.
Part of our injectable steroids:
|Propionat 100 (Testosterone Propionate)||100mg/ml|
|Propionat 200 (Testosterone Propionate)||200mg/ml|
|Enanject 250 (Testosterone Enanthate)||250mg/ml|
|Cypoject 250 (Testosterone Cypionate)||250mg/ml|
|Undecanoate 500(Testosterone Undecanoate)||500mg/ml|
|Anadrol 50 (Oxymetholone)||50mg/ml|
|Anavar 50 (Oxandrolone)||50mg/ml|
|Deca-Durabolin 200 (Nandrolone Decanoate)||200mg/ml|
|Deca-Durabolin 250 (Nandrolone Decanoate)||250mg/ml|
|NPP 200 (Nandrolone Phenylpropionate)||200mg/ml|
|Trenabol 100 (Trenbolone Base)||100mg/ml|
|Trenabolic 100 (Trenbolone Acetate)||100mg/ml|
|Trenabolic 200 (Trenbolone Acetate)||200mg/ml|
|Trenaject 60 (Trenbolone Enanthate)||60mg/ml|
|Trenaject 100 (Trenbolone Enanthate)||100mg/ml|
|Trenaject 150 (Trenbolone Enanthate)||150mg/ml|
|Trenaject 200 (Trenbolone Enanthate)||200mg/ml|
|Parabolone 50 (Trenbolone hexahydrobenzylcarbonate)||500mg/ml|
|Masteron 100 (Drostanolone propionate)||100mg/ml|
|Masteron 150 (Drostanolone propionate)||150mg/ml|
|Masteron 200 (Drostanolone Enanthate)||200mg/ml|
|Primoject 100 (Methenolone Enanthate)||100mg/ml|
|Nandrolone 200 (Nandrolone Cypionate)||200mg/ml|
|Boldenone 200 (Boldenone Cypionate)||200mg/ml|
|Boldenone 200 (Boldenone undecylenate/Equipoise)||200mg/ml|
|Primoject 100 (Methenolone Acetate/Primobolone)||100mg/ml|
|Primoject 100 (Methenolone Enanthate/Primobolan)||100mg/ml|
|Winstrol 50 (Stanozolol)||50mg/ml|