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CAS 55-31-2 Pharmaceutical Raw Materials L-Epinephrine Hydrochloride / L-Epinephrine Hcl

CAS 55-31-2 Pharmaceutical Raw Materials L-Epinephrine Hydrochloride / L-Epinephrine Hcl

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Pharmaceutical Raw Materials L-Epinephrine Hydrochloride / L-Epinephrine Hcl CAS 55-31-2
 
1) L-Epinephrine Hydrochloride Details

 

Product NameL-Epinephrine Hydrochloride
Synonyms

(-)-adrenalinehydrochlorid;3,4-dihydroxy-alpha-((methylamino)methyl)-

,hydrochloride,(-)-benzylalcoho;4-(1-hydroxy-2-(methylamino)ethyl)-,

hydrochloride,(r)-2-benzenediol;epinephrinechloride;gelatin-epinephrine;l-1-(3,4-dihydroxyphenyl)-2-methylamino-1-ethanolhydrochloride;l-adrenalinechloride;l-adrenalinehydrochloride

CAS

55-31-2

EINECS

200-230-3

MF

C9H14ClNO3

MW

219.67

Molecular Structure
AssayUSP
Character

White crystals. Used medically as a cardiostimulant.

Air & Water Reactions

Water soluble [Merck].

Usage

Used medically as a cardiostimulant.

Reactivity Profile

L-Epinephrine hydrochloride is readily destroyed by alkalis and oxidizing agents.

Health Hazard SYMPTOMS

Adverse reactions include restlessness; anxiety; headache; tremor; weakness; dizziness; pallor; respiratory difficulties; palpitation; nausea and vomiting.

Fire Hazard

Flash point data for L-Epinephrine hydrochloride are not available, but L-Epinephrine hydrochloride is probably combustible.

Packing1kg/bag


2)  L-Epinephrine Hydrochloride Usage

 

Epinephrine Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation.

 

3) L-Epinephrine Hydrochloride COA

 

ItemsRequirementsResults
DescriptionWhite or almost white crystalline powderComplies
IdentificationPositiveComplies
Loss on drying≤0.5%0.33%
Specific Rotation– 1.0° ~ +1.0°
Limit of Adrenalone ≤A310nm0.200.013
Limit of Norepinephrine ≤%4.0%N.D
Organic volatile impurties≤%0.5%Complies
Residue On Ignition ≤%0.5%0.06%
Assay97.0%-102.0%99.6%
Conclusion Meets the requirements


4) L-Epinephrine Hydrochloride Application


The relaxation of bronchial smooth muscle, to relieve bronchial spasm, control asthma.
The heart excited, increase the myocardial contraction and contraction velocity, for cardiac resuscitation.
As for severe allergic reactions, such as anaphylactic shock, relieve bronchial spasm, urticaria, angioneurotic edema, skin pruritus.
To be added to the local anesthetic solution can prolong the time of spinal nerve block.
The correction is mainly caused by the low cardiac output syndrome after extracorporeal circulation.
Which Is used for the treatment of hypoglycemia, such as insulin effect caused by excessive.
The local administration, vascular contraction to alleviate binding membrane hyperemia, and surface control of skin and mucosa bleeding.
 
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