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Raw Powder Indole-3-Carboxylic Acid with Factory Direct Supply CAS NO.771-50-6

Raw Powder Indole-3-Carboxylic Acid with Factory Direct Supply CAS NO.771-50-6

Brand Name: SBJ
Certification: SGS,ISO9001,UKAS
Model Number: 93-55-0
Minimum Order Quantity: 10g
Delivery Time: within 12hours after payment
Payment Terms: T/T, Western Union, MoneyGram, Bitecoin
Zhuhaishi Shuangbojie Technology Co.,ltd
Verified Supplier
Zhuhai Guangdong China
Business type: Manufacturer
Yuehai International Garden,Zhuhai City,Guangdong Province,519000
Supplier`s last login times: within 42 hours

Product Info:

Chemical nameIndole-3-carboxylic acid
CAS No.771-50-6
SynonymIndole-3-carboxylic acid
Molecular FormulaC9H7NO2
Molecular Weight161.15
Store atRoom temperature
Purity99% min
Appearanceyellow powder

Cabergoline

Cabergoline CAS No: 81409-90-7
Cabergoline M.W: 451.6
Cabergoline Formula: C26H37N5O2
Cabergoline Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Cabergoline Purity: 99 %min
Cabergoline Storage: Store at +4°C
Cabergoline Appearance: White powder


Product Name:CabergolineBatch No201505001
Analysis Date2015. 06. 01MFG Date2015. 05. 07
Quantity298gCAS81409-90-7
Standard:EP6.0/ USP38packing-

ITEMLIMITRESULT
DescriptionWhite or almost white crystarlline powderConforn
Identify1. IR complies
2. X-Ray complies
3. HPLC complies
Conforn
Conforn
Conforn
WaterNo more than 0.5%0.2%
Reiated substances1.Allylamide (USP,rel,D) no more than 0.10%
2. Allyl DHLA(USP,rel,D) no more than 0.15%;
3.Cabergoline oxide no more than 0.10% ;
4.Other impurities individually no more than 0.10% ;
5.Total no more than 0.50% ;
0.02%
Less than 0.02%
Less than 0.02%
Less than 0.02%

0.05%
Assay(HPLC)98.0-102.0%100.5%
Opdical rotation-83.0-- -77.0-78
Residual Solvents1.Dichloromethane no more than 100ppm;
2.Acetone no more than200ppm;
3.Tert-butylmethylether no more than 200ppm;
4.Xylene no more than 1500ppm;
5.HEptane no more than 1000ppm;
Less than30ppm
Less than20ppm
Less than10ppm
110ppm
Less than30ppm
Residue on ignitionNO more than0.10 %0.02%
Heavy metalsNO more than 20ppm2ppm
Partcle size90%af particles no mone than 80μmConform
Bulk Density0.2~0.35g/em0.33g/em
ConclusionConforn with EP6.0/ USP38
SupervisorYang DeXinAnalystChenJiaoJiao


Description

Cabergoline is used to treat different types of medical problems that occur when too much of the hormone prolactin is produced. It can be used to treat certain menstrual problems, fertility problems in men and women, and pituitary prolactinomas (tumors of the pituitary gland).It works by stopping the brain from making and releasing the prolactin hormone from the pituitary gland.

Cabergoline use is usually stopped when prolactin levels are normal for 6 months. It may be given again if symptoms of too much prolactin occur again.

Originally introduced by the anti-aging community to the bodybuilding world, this dopamine receptor agonist has the chemical name of 1-[(6-allylergolin-8?-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea and tablets of this drug include 0.5 mg of cabergoline and the list of inactive ingredients includes leucine, USP, lactose, and NF.
Dostinex-Cabergoline has a chemical name of 1-[(6-allylergolin-8?-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea. The empirical formula for this drug is C26H37N5O2 and its molecular weight is 451.62.



Application

The biggest reason why Cabergoline is admired by amateur and professional athletes is because it helps them reduce or eliminate the risks associated with excess prolactin that is common with use of harsh and aromatizable steroids like Trenbolone and Deca Durabolin. Furthermore, this drug is also useful for treating sexual dysfunction caused by excess prolactin besides gaining an erection between orgasms and reducing recovery time after intense workouts or weight training and strength training exercises. In addition to these advantages, the use of Dostinex is equally beneficial to combat estrogenic side effects such as oily skin, acne, gynecomastia, and bloating and treating health complications like galactorrhea and sexual dysfunction. It is also routinely indicated to patients with Parkinson's disease as it has the potential to work on information pathways and nervous system of the body. Dostinex is also admired for its ability to make athletes feel 'full' that helps in minimizing food cravings without dieting discomfort.

Cabergoline is an ergot medication and works by blocking the release of prolactin from the pituitary gland.Dostinex is used to treat Parkinson's disease, to prevent women producing milk when they want to stop breast feeding(hyperprolactinemia), Cabergoline can lower prolactin levels in patients with a pituitary tumor. Cabergoline is also sometimes used to help men with sexual dysfunction.

1. hyperprolactinemia
2. adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
3. monotherapy of Parkinson's disease in the early phase;
4. combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's disease;
5. in some countries also: ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea);
6. treatment of uterine fibroids.
7. adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases;
8.and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when hormone secretion can not be sufficiently controlled by other methods;
9. Cushing's disease - cabergoline may be used to lower ACTH levels and cause regression of ACTH producing pituitary adenomas;
10. other pituitary adenomas - cabergoline has demonstrated certain efficacy in controlling or reducing other kinds of pituitary adenomas, as well as silent or non-functional adenomas.



Usage

Use cabergoline as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take cabergoline by mouth with or without food.
It may be helpful to mark on a calendar which days you are supposed to take cabergoline.
If you miss a dose of cabergoline, contact your doctor right away.
Ask your health care provider any questions you may have about how to use cabergoline.



Dosage

Parkinson's disease: Monotherapy: Initial dose should be 0.5 mg daily. The usual maintenance dose is 2 to 4 mg daily. Combination therapy: Usually 2 to 6 mg daily.
Tumors of the pituitary gland and other hyperprolactinemic conditions: Initially 0.5 mg per week, slowly titrated to 4.5 mg per week, if necessary.
Ablactation: According to specific treatment scheme.



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About us

Zhuhaishi Shuangbojie Technology Co., Ltd, a leading manufacturer and supplier of fine chemicals in China, is located in Zhuhai City Guangdong Province. Our company's various chemical raw material products have stable and reliable quality, it is mainly sold to pharmacy company and health care company in abroad, like USA, Canada, UK,
Brazil, Netherlands, Ireland, New Zealand, Austria, Australia and so on.
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